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Title

Accurate Monte Carlo modeling and performance assessment of the X-PET subsystem of the FLEX triumph preclinical PET/CT scanner

Authors
Zeraatkar, N
Kamali-Asl, A R
Published in Medical Physics. 2011, vol. 38, no. 3, p. 1217-25
Abstract X-PET is a commercial small animal PET scanner incorporating several innovative designs to achieve improved performance. It is employed as a PET subsystem in the FLEX Triumph preclinical PET/CT scanner, the first commercial small animal PET/CT scanner worldwide. The authors report on a novel Monte Carlo (MC) model designed for the evaluation of performance parameters of the X-PET METHODS: The Geant4 Application for Tomographic Emission (GATE) MC code was used as a simulation tool. The authors implemented more accurate modeling of the geometry of detector blocks and associated electronic chains, including dead-time and time-independent parameters, compared to previously presented MC models of the X-PET scanner. Validation of the MC model involved comparison between simulated and measured performance parameters of the X-PET, including spatial resolution, sensitivity, and noise equivalent count rate (NECR). Thereafter, various simulations were performed to assess scanner performance parameters according to NEMA NU 4-2008 standards with the aim to present a reliable Monte Carlo platform for small animal PET scanner design optimization.
Keywords AnimalsImage Processing, Computer-AssistedMiceMonte Carlo MethodPhantoms, ImagingPositron-Emission Tomography/instrumentation/methodsRatsReproducibility of ResultsScattering, RadiationTomography, X-Ray Computed/instrumentation/methods
Identifiers
PMID: 21520834
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Article (Published version) (641 Kb) - public document Free access
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Research group Imagerie Médicale (TEP et TEMP) (542)
Project FNS: 31003A-125246
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(ISO format)
ZERAATKAR, N et al. Accurate Monte Carlo modeling and performance assessment of the X-PET subsystem of the FLEX triumph preclinical PET/CT scanner. In: Medical Physics, 2011, vol. 38, n° 3, p. 1217-25. https://archive-ouverte.unige.ch/unige:23499

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Deposited on : 2012-10-19

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