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Place du cancer parmi les facteurs de risque de la maladie thromboembolique veineuse

Descourt, R.
Carrier, M.
Le Gal, G.
Published in Pathologie Biologie. 2008, vol. 56, no. 4, p. 178-183
Abstract There is a strong association between cancer and venous thromboembolism (VTE). Cancer patients have a seven-fold higher risk of developing VTE as compared with noncancer patients. In the year following the diagnosis of cancer, 1.6% of patients will develop a VTE event. VTE is one of the main cause of death in cancer patients, accounting for about 15% of deaths. On the other hand, cancer patients represent 15 to 20% of all VTE cases. Beyond classical risk factors for VTE, specific risk factors are associated with VTE in cancer patients: tumor site, stage, histological type, treatment, duration of the disease. VTE occurrence is associated with a poorer outcome in cancer patients: a reduced survival is observed in cancer patients with VTE as compared to non-VTE cancer patients. This impact of VTE on prognosis varies according to cancer characteristics. Conversely, evolution of VTE is different in cancer patients, with a higher short-term risk of mortality and a higher risk of recurrences, including on anticoagulant treatment, also modulated by cancer characteristics.
Keywords FemaleHumansIncidenceMaleNeoplasms/classification/complicationsPrognosisRisk FactorsVenous Thromboembolism/epidemiology
PMID: 18325691
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DESCOURT, R. et al. Place du cancer parmi les facteurs de risque de la maladie thromboembolique veineuse. In: Pathologie Biologie, 2008, vol. 56, n° 4, p. 178-183. https://archive-ouverte.unige.ch/unige:2228

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Deposited on : 2009-07-17

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