Supersaturation: enhancement of skin penetration and permeation of a lipophilic drug

Moser, Katrin; Kriwet, K; Froehlich, C; Kalia, Yogeshvar; Guy, Richard H.

doi:10.1023/A:1010948630296

Scientific article

English

Supersaturation: enhancement of skin penetration and permeation of a lipophilic drug

ContributorsMoser, Katrin; Kriwet, K; Froehlich, C; Kalia, Yogeshvar

; Guy, Richard H.

Published inPharmaceutical research, vol. 18, no. 7, p. 1006-1011

Publication date2001

Abstract

To increase the dermal delivery of a lipophilic model compound (LAP), and to deduce the underlying mechanism of enhanced absorption.

Keywords

Animals
Drug Delivery Systems/methods
Epidermis/metabolism
Lipids/administration & dosage/pharmacokinetics
Permeability
Pharmaceutical Vehicles/administration & dosage/pharmacokinetics
Propylene Glycol/administration & dosage/pharmacokinetics
Skin Absorption/physiology
Swine

Affiliation entities

Faculté des sciences / Section des sciences pharmaceutiques

Citation (ISO format)

MOSER, Katrin et al. Supersaturation: enhancement of skin penetration and permeation of a lipophilic drug. In: Pharmaceutical research, 2001, vol. 18, n° 7, p. 1006–1011. doi: 10.1023/A:1010948630296

Article (Published version)

Identifiers

PID : unige:21958
DOI : 10.1023/A:1010948630296
PMID : 11496937

Commercial URLhttp://www.springerlink.com/content/g1724106184k2626/?MUD=MP

ISSN of the journal0724-8741

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Supersaturation: enhancement of skin penetration and permeation of a lipophilic drug

To increase the dermal delivery of a lipophilic model compound (LAP), and to deduce the underlying mechanism of enhanced absorption.

Technical informations