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Ventilation practices in the neonatal intensive care unit: a cross-sectional study

van Kaam, Anton H.
Borensztajn, Dorine
De Jaegere, Anne P.
Published in The Journal of pediatrics. 2010, vol. 157, no. 5, p. 767-771 e761-763
Abstract OBJECTIVE: To assess current ventilation practices in newborn infants. STUDY DESIGN: We conducted a 2-point cross-sectional study in 173 European neonatal intensive care units, including 535 infants (mean gestational age 28 weeks and birth weight 1024 g). Patient characteristics, ventilator settings, and measurements were collected bedside from endotracheally ventilated infants. RESULTS: A total of 457 (85%) patients were conventionally ventilated. Time cycled pressure-limited ventilation was used in 59% of these patients, most often combined with synchronized intermittent mandatory ventilation (51%). Newer conventional ventilation modes like volume targeted and pressure support ventilation were used in, respectively, 9% and 7% of the patients. The mean tidal volume, measured in 84% of the conventionally ventilated patients, was 5.7 +/- 2.3 ml/kg. The mean positive end-expiratory pressure was 4.5 +/- 1.1 cmH(2)O and rarely exceeded 7 cmH(2)O. CONCLUSIONS: Time cycled pressure-limited ventilation is the most commonly used mode in neonatal ventilation. Tidal volumes are usually targeted between 4 to 7 mL/kg and positive end-expiratory pressure between 4 to 6 cmH(2)O. Newer ventilation modes are only used in a minority of patients.
Keywords Cross-Sectional StudiesFemaleHumansInfant, NewbornIntensive Care Units, NeonatalMaleProspective StudiesRespiration, Artificial/*methodsRespiratory Insufficiency/*therapy
PMID: 20619854
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Research group Maladies pulmonaires aigues et pathologies cardiaques congénitales (697)
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VAN KAAM, Anton H. et al. Ventilation practices in the neonatal intensive care unit: a cross-sectional study. In: The Journal of Pediatrics, 2010, vol. 157, n° 5, p. 767-771 e761-763. doi: 10.1016/j.jpeds.2010.05.043 https://archive-ouverte.unige.ch/unige:21362

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Deposited on : 2012-05-23

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