UNIGE document Scientific Article - Review
previous document  unige:21273  next document
add to browser collection
Title

Sinusoidal obstruction syndrome

Author
Published in Clinics in Liver Disease. 2010, vol. 14, no. 4, p. 651-668
Abstract Sinusoidal obstruction syndrome (SOS), formerly named venoocclusive disease, is a well-known complication of hematopoietic stem cell transplantation and ingestion of food or drinks contaminated by pyrrolizidine alkaloids. Many other drugs and toxins have been associated with SOS, including several chemotherapeutic agents and immunosuppressors. SOS contributes to significant morbidity and mortality in all these settings. This review describes the histologic lesions of SOS, details its pathogenesis as it is understood today, specifies the recent data on its causes and how it may influence clinical management of colorectal liver metastases, and discusses the current knowledge on diagnosis and preventive options.
Keywords AnimalsHepatic Veno-Occlusive Disease/*etiology/*pathologyHumans
Identifiers
PMID: 21055688
Full text
Structures
Research group Métastases du foie (657)
Citation
(ISO format)
RUBBIA-BRANDT, Laura. Sinusoidal obstruction syndrome. In: Clinics in Liver Disease, 2010, vol. 14, n° 4, p. 651-668. https://archive-ouverte.unige.ch/unige:21273

199 hits

0 download

Update

Deposited on : 2012-05-23

Export document
Format :
Citation style :