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Human papillomavirus-associated oropharyngeal cancer: a new clinical entity

Nguyen, N. P.
Chi, A.
Nguyen, L. M.
Ly, B. H.
Karlsson, U.
Published in QJM. 2010, vol. 103, no. 4, p. 229-236
Abstract The incidence of oropharyngeal cancers is rising worldwide in both nonsmokers and nondrinkers. Epidemiology studies suggest a strong association between human papillomavirus (HPV) 16 infection, changing sexual behavior and cancer development. Despite initial presentation with locally advanced disease and poorly differentiated histology, HPV-associated oropharyngeal carcinoma is associated with a good prognosis because its response to chemotherapy and radiation. Clinicians should be aware of the risk of oropharyngeal cancer in young people to avoid unnecessary delay in diagnosis and treatment. A history of oral sex should be elicited in young patients with enlarged neck nodes and/or tonsillar masses.
Keywords AdultDNA, Viral/geneticsFemale*Human papillomavirus 16/geneticsHumansMaleOropharyngeal Neoplasms/epidemiology/therapy/*virologyPapillomavirus Infections/epidemiology/therapy/*virologyYoung Adult
PMID: 20015950
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NGUYEN, N. P. et al. Human papillomavirus-associated oropharyngeal cancer: a new clinical entity. In: QJM, 2010, vol. 103, n° 4, p. 229-236. doi: 10.1093/qjmed/hcp176 https://archive-ouverte.unige.ch/unige:21182

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Deposited on : 2012-05-23

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