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Treatment of velopharyngeal insufficiency by autologous fat injection

Hohlfeld, Judith
Pasche, Philippe
Published in European Archives of Oto-Rhino-Laryngology. 2010, vol. 267, no. 6, p. 977-983
Collection Open Access - Licence nationale Springer
Abstract Velopharyngeal insufficiency (VPI) is a structural or functional trouble, which causes hypernasal speech. Velopharyngeal flaps, speech therapy and augmentation pharyngoplasty, using different implants, have all been used to address this trouble. We hereby present our results following rhinopharyngeal autologous fat injection in 18 patients with mild velopharyngeal insufficiency (12 soft palate clefts, 4 functional VPI, 2 myopathy). 28 injections were carried out between 2004 and 2007. The degree of hypernasal speech was evaluated pre- and postoperatively by a speech therapist and an ENT specialist and quantified by an acoustic nasometry (Kay Elemetrics). All patients were exhaustively treated with preoperative speech therapy (average, 8 years). The mean value of the nasalance score was 37% preoperatively and 23% postoperatively (p = 0.015). The hypernasality was reduced postoperatively in all patients (1-3 degrees of the Borel-Maisonny score). There were no major complications, two minor complications (one hematoma, one cervical pain). The autologous fat injection is a simple, safe, minimally invasive procedure. It proves to be efficient in cases of mild velopharyngeal insufficiency or after a suboptimal velopharyngoplasty.
Keywords Adipose Tissue/*transplantationAdolescentAdultChildCleft Palate/surgeryDiGeorge Syndrome/surgeryFemaleFollow-Up StudiesHumansMaleMiddle AgedPhonation/physiologyPostoperative Complications/etiologySound SpectrographySpeech IntelligibilityVelopharyngeal Insufficiency/etiology/*surgeryVoice Disorders/etiology/surgeryVoice Quality/physiologyYoung Adult
PMID: 20033195
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LEUCHTER, Igor et al. Treatment of velopharyngeal insufficiency by autologous fat injection. In: European Archives of Oto-Rhino-Laryngology, 2010, vol. 267, n° 6, p. 977-983. doi: 10.1007/s00405-009-1157-7 https://archive-ouverte.unige.ch/unige:21084

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Deposited on : 2012-05-23

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