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Kaposi's sarcoma after repeated surgical procedures in an immunocompetent patient: the lymphatic hypothesis |
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Authors | ![]() | |
Published in | Dermatology. 2010, vol. 221, no. 4, p. 313-316 | |
Abstract | A 63-year-old Swiss patient developed acquired nodules on his right palm after 3 localized surgeries, called 'needle fasciotomy', for Dupuytren's disease. Kaposi's sarcoma (KS) was diagnosed in a biopsy of a nodule. A positive immunolabeling and serology for human herpesvirus 8 has been found, but human immunodeficiency virus and hepatitis C identification remained negative. The nodules were limited to the surgically traumatized area. This first report of a nonimmunocompromised patient developing a KS after repeated surgeries in a unique peculiar localized area with a dense lymphatic network sustains the hypothesis that tissue alterations involving the lymphatic system could play a central role in the occurrence of KS. | |
Keywords | Aminoquinolines/therapeutic use — Antineoplastic Agents/therapeutic use — Biopsy — Dupuytren Contracture/immunology/*surgery/virology — Herpesvirus 8, Human/drug effects/immunology/isolation & purification — Humans — Immunocompetence/immunology — Lymphatic System/drug effects/immunology/virology — Male — Middle Aged — Sarcoma, Kaposi/*diagnosis/drug therapy/immunology/pathology/virology — Skin Neoplasms/*diagnosis/drug therapy/immunology/virology — Treatment Outcome | |
Identifiers | DOI: 10.1159/000321193 PMID: 21051867 | |
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Structures |
Faculté de médecine / Section de médecine fondamentale / Département de physiologie cellulaire et métabolisme |
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Research groups | Anatomie clinique (134) Groupe Becker Minerva (imagerie ORL) (683) Groupe Desmeules Jules (pharmacologie/toxicologie) (567) Rôle du CD44 (809) | |
Citation (ISO format) | KOSTAKI, Maria et al. Kaposi's sarcoma after repeated surgical procedures in an immunocompetent patient: the lymphatic hypothesis. In: Dermatology, 2010, vol. 221, n° 4, p. 313-316. doi: 10.1159/000321193 https://archive-ouverte.unige.ch/unige:21050 |