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Think (Gram) negative!

Published in Critical Care. 2010, vol. 14, no. 3, 171
Abstract The increasing prevalence of multiresistant Gram-negative bacteria of the Enterobacteriaceae family in Europe is a worrisome phenomenon. Extended spectrum betalactamase-producing Escherichia coli strains are widespread in the community and are frequently imported into the hospital. Of even more concern is the spread of carbapenem-resistant strains of Klebsiella spp. from regions where they are already endemic. Antibiotic use is a main driver of antibiotic resistance, which again increases broad spectrum antibiotic use, resulting in a vicious circle that is difficult to interrupt. The present commentary highlights important findings of a surveillance study of antimicrobial use and resistance in German ICUs over 8 years with a focus on Gram-negative resistance.
Keywords Anti-Bacterial Agents/therapeutic useDrug Resistance, Bacterial/*drug effects*Drug Resistance, MultipleGermanyGram-Negative Bacteria/*drug effectsGram-Negative Bacterial Infections/drug therapyHumansIntensive Care UnitsPhysician's Practice PatternsPopulation Surveillance
PMID: 20587087
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Research group Groupe Harbarth Stephan (Staphylocoques dorés résistants à la méthicilline) (866)
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HUTTNER, Benedikt, HARBARTH, Stéphan Juergen. Think (Gram) negative!. In: Critical Care, 2010, vol. 14, n° 3, p. 171. doi: 10.1186/cc9041 https://archive-ouverte.unige.ch/unige:21018

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Deposited on : 2012-05-23

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