Osteoarthritis: Small studies overestimate the benefit of therapies for OA

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Title		Osteoarthritis: Small studies overestimate the benefit of therapies for OA
Authors		Finckh, Axel Tramer, Martin
Published in		Nature reviews. Rheumatology. 2010, vol. 6, no. 11, p. 617-618
Abstract		a meta-epidemiological study has revealed that the inclusion of small studies in meta-analyses of osteoarthritis interventions could lead to an overestimation of the benefit of these interventions. Does this mean meta-analyses should be restricted to trials with large sample sizes?
Keywords		Humans — Meta-Analysis as Topic — Osteoarthritis/therapy — Publication Bias — *Randomized Controlled Trials as Topic — Reproducibility of Results — Sample Size — Treatment Outcome
Identifiers		DOI: 10.1038/nrrheum.2010.162 PMID: 21037558
Full text		Article - Limited access to UNIGE
Structures		Faculté de médecine / Section de médecine clinique / Département de médecine Faculté de médecine / Section de médecine clinique / Département d'anesthésiologie, pharmacologie, soins intensifs et urgences
Research groups		La Médecine Périopératoire et l'anesthésie (70) Mécanisme de l'inflammation articulaire (44)
Citation (ISO format)		FINCKH, Axel, TRAMER, Martin. Osteoarthritis: Small studies overestimate the benefit of therapies for OA. In: Nature reviews. Rheumatology, 2010, vol. 6, n° 11, p. 617-618. doi: 10.1038/nrrheum.2010.162 https://archive-ouverte.unige.ch/unige:20935

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Deposited on : 2012-05-23

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