Osteoarthritis: Small studies overestimate the benefit of therapies for OA

Finckh, Axel; Tramer, Martin

doi:10.1038/nrrheum.2010.162

Article scientifique

Anglais

Osteoarthritis: Small studies overestimate the benefit of therapies for OA

Contributeurs/tricesFinckh, Axel; Tramer, Martin

Publié dansNature reviews. Rheumatology, vol. 6, no. 11, p. 617-618

Date de publication2010

Résumé

a meta-epidemiological study has revealed that the inclusion of small studies in meta-analyses of osteoarthritis interventions could lead to an overestimation of the benefit of these interventions. Does this mean meta-analyses should be restricted to trials with large sample sizes?

Mots-clés

Humans
*Meta-Analysis as Topic
Osteoarthritis/*therapy
Publication Bias
*Randomized Controlled Trials as Topic
Reproducibility of Results
Sample Size
Treatment Outcome

Structure d'affiliation

Groupe de recherche

Citation (format ISO)

FINCKH, Axel, TRAMER, Martin. Osteoarthritis: Small studies overestimate the benefit of therapies for OA. In: Nature reviews. Rheumatology, 2010, vol. 6, n° 11, p. 617–618. doi: 10.1038/nrrheum.2010.162

Article

Identifiants

PID : unige:20935
DOI : 10.1038/nrrheum.2010.162
PMID : 21037558

ISSN du journal1759-4790

621vues

0téléchargements

Création23.05.2012 08:45:30

Première validation23.05.2012 08:45:30

Heure de mise à jour14.03.2023 17:33:01

Changement de statut14.03.2023 17:33:01

Dernière indexation12.02.2024 20:12:14

Archive ouverte UNIGE

Osteoarthritis: Small studies overestimate the benefit of therapies for OA

a meta-epidemiological study has revealed that the inclusion of small studies in meta-analyses of osteoarthritis interventions could lead to an overestimation of the benefit of these interventions. Does this mean meta-analyses should be restricted to trials with large sample sizes?

Informations techniques