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Osteoarthritis: Small studies overestimate the benefit of therapies for OA |
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Published in | Nature reviews. Rheumatology. 2010, vol. 6, no. 11, p. 617-618 | |
Abstract | a meta-epidemiological study has revealed that the inclusion of small studies in meta-analyses of osteoarthritis interventions could lead to an overestimation of the benefit of these interventions. Does this mean meta-analyses should be restricted to trials with large sample sizes? | |
Keywords | Humans — *Meta-Analysis as Topic — Osteoarthritis/*therapy — Publication Bias — *Randomized Controlled Trials as Topic — Reproducibility of Results — Sample Size — Treatment Outcome | |
Identifiers | PMID: 21037558 | |
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Research groups | La Médecine Périopératoire et l'anesthésie (70) Mécanisme de l'inflammation articulaire (44) | |
Citation (ISO format) | FINCKH, Axel, TRAMER, Martin. Osteoarthritis: Small studies overestimate the benefit of therapies for OA. In: Nature reviews. Rheumatology, 2010, vol. 6, n° 11, p. 617-618. doi: 10.1038/nrrheum.2010.162 https://archive-ouverte.unige.ch/unige:20935 |