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Title

Segmental duodenectomy for gastrointestinal stromal tumor of the duodenum

Authors
Ostermann, Sandrine
Pugin, François
Published in World Journal of Gastroenterology. 2010, vol. 16, no. 22, p. 2788-2792
Abstract AIM: To evaluate the results of segmental duodenectomy (SD) and pancreaticoduodenectomy (PD) for duodenal gastrointestinal stromal tumor (GIST) and help clinicians with surgical management. METHODS: All patients who underwent surgery for non-metastatic GIST of the duodenum in a single institution since 2000 were prospectively followed up. Seven patients (median age 51 years, range: 41-73 years) were enrolled: five underwent SD and two underwent PD. RESULTS: All the patients had a complete resection (R0), with no postoperative morbidity and mortality. Among the SD group, GIST was classified as low risk in two patients, intermediate risk in two, and high risk in one, according to the Fletcher scale, (vs two high risk patients in the PD group). With a median follow-up of 41 (18-85) mo, disease-free survival (DFS) rates were 100% after SD and 0% after PD (P < 0.05). The median DFS was 13 mo in the PD group. CONCLUSION: Whenever associated with clear surgical margins, SD is a reliable and curative option for most duodenal GISTs, and is compatible with long-term DFS.
Keywords AdultAgedDigestive System Surgical Procedures/ methodsDisease-Free SurvivalGastrointestinal Stromal Tumors/pathology/ surgeryHumansMiddle AgedPancreaticoduodenectomy/ methodsTreatment Outcome
Identifiers
PMID: 20533599
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Other version: http://www.wjgnet.com/1007-9327/index.jsp
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Research group Chirurgie viscérale (104)
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BUCHS, Nicolas et al. Segmental duodenectomy for gastrointestinal stromal tumor of the duodenum. In: World Journal of Gastroenterology, 2010, vol. 16, n° 22, p. 2788-2792. https://archive-ouverte.unige.ch/unige:20814

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Deposited on : 2012-05-23

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