An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits
Contributeurs/tricesHsu, Yi-Hsiang; Zillikens, M Carola; Wilson, Scott G.; Farber, Charles R.; Demissie, Serkalem; Soranzo, Nicole; Bianchi, Estelle; Grundberg, Elin; Liang, Liming; Richards, J Brent; Estrada, Karol; Zhou, Yanhua; van Nas, A.; Moffatt, M. F.; Zhai, G.; Hofman, A.; van Meurs, J. B.; Pols, H. A.; Price, R. I.; Nilsson, O.; Pastinen, T.; Cupples, L. A.; Lusis, A. J.; Schadt, E. E.; Ferrari, Serge Livio; Uitterlinden, A. G.; Rivadeneira, F.; Spector, T. D.; Karasik, D.; Kiel, D. P.
Publié dansPLOS genetics, vol. 6, no. 6, e1000977
Date de publication2010
Résumé
Mots-clés
- Animals
- Bone Density
- Cells, Cultured
- Female
- Gene Expression Profiling
- Genetic Loci
- *Genetic Predisposition to Disease
- Genome-Wide Association Study
- Humans
- Male
- Mice
- Mice, Inbred C57BL
- Osteoporosis/*genetics/physiopathology
- *Polymorphism, Single Nucleotide
- Transcription, Genetic
Groupe de recherche
Citation (format ISO)
HSU, Yi-Hsiang et al. An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits. In: PLOS genetics, 2010, vol. 6, n° 6, p. e1000977. doi: 10.1371/journal.pgen.1000977
Fichiers principaux (1)
Article (Accepted version)
Identifiants
- PID : unige:20635
- DOI : 10.1371/journal.pgen.1000977
- PMID : 20548944
ISSN du journal1553-7390