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Pancréatite autoimmune

Published in Revue médicale suisse. 2010, vol. 6, no. 261, p. 1662-1666
Abstract Autoimmune pancreatitis (ALP) represents a distinct form of chronic pancreatitis initially described in Japan but now reported worldwide. AIP often presents with obstructive jaundice/pancreatic mass as well as pancreatic exocrine and endocrine insufficiency. Histologically, it is characterised by a lymphoplasmacytic infiltrate with fibrosis. The disease responds readily to steroids in 70-80% of cases. Given the absence of unified diagnostic criteria, the diagnosis of AIP proves difficult. In particular, distinguishing ALP from pancreatic or biliary cancer remains a challenging task. In order to avoid unnecessary resections for an otherwise benign and easily treatable condition, it is urgent to refine diagnostic criteria and to reach an international consensus.
Keywords Autoimmune Diseases/*diagnosis/drug therapy/epidemiologyDiagnosis, DifferentialEurope/epidemiologyExocrine Pancreatic Insufficiency/diagnosis/immunologyGlucocorticoids/therapeutic useHumansJaundice, Obstructive/diagnosis/immunologyPancreatitis, Chronic/*diagnosis/drug therapy/epidemiology/*immunologyTreatment Outcome
PMID: 20939400
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Research group Physiopathologie de la pancréatite aiguë (601)
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VONLAUFEN, Alain, FROSSARD, Jean-Louis. Pancréatite autoimmune. In: Revue médicale suisse, 2010, vol. 6, n° 261, p. 1662-1666. https://archive-ouverte.unige.ch/unige:20587

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Deposited on : 2012-05-22

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