en
Scientific article
Review
French

Pancréatite autoimmune

Other titleAutoimmune pancreatitis
Published inRevue médicale suisse, vol. 6, no. 261, p. 1662-1666
Publication date2010
Abstract

Autoimmune pancreatitis (ALP) represents a distinct form of chronic pancreatitis initially described in Japan but now reported worldwide. AIP often presents with obstructive jaundice/pancreatic mass as well as pancreatic exocrine and endocrine insufficiency. Histologically, it is characterised by a lymphoplasmacytic infiltrate with fibrosis. The disease responds readily to steroids in 70-80% of cases. Given the absence of unified diagnostic criteria, the diagnosis of AIP proves difficult. In particular, distinguishing ALP from pancreatic or biliary cancer remains a challenging task. In order to avoid unnecessary resections for an otherwise benign and easily treatable condition, it is urgent to refine diagnostic criteria and to reach an international consensus.

Keywords
  • Autoimmune Diseases/*diagnosis/drug therapy/epidemiology
  • Diagnosis, Differential
  • Europe/epidemiology
  • Exocrine Pancreatic Insufficiency/diagnosis/immunology
  • Glucocorticoids/therapeutic use
  • Humans
  • Jaundice, Obstructive/diagnosis/immunology
  • Pancreatitis, Chronic/*diagnosis/drug therapy/epidemiology/*immunology
  • Treatment Outcome
Citation (ISO format)
VONLAUFEN, Alain, FROSSARD, Jean-Louis. Pancréatite autoimmune. In: Revue médicale suisse, 2010, vol. 6, n° 261, p. 1662–1666.
Identifiers
ISSN of the journal1660-9379
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