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Scientific article
Review
English

Nasal provocation test: how to maximize its clinical use?

Contributors

Tantilipikorn, Pongsakorn; Vichyanond, Pakit; Lacroix, Jean-Sylvain

Published in

Asian Pacific Journal of Allergy and Immunology, vol. 28, no. 4, p. 225-231

Publication date

2010

Abstract

In order to diagnose allergic rhinitis (AR), skin prick tests and serum specific IgE level are the most common used methods. But there are some conditions which the results of both methods do not correlate with the clinical presentation of AR. Nasal provocation test is the method of detecting local IgE at the shock organ. There are some variations of NPT in terms of dosage, allergen administration, evaluation and scoring system. This article summarized the usefulness of NPT, its indication and contraindication, dosage and instillation techniques for allergens and evaluation of outcome in the hope that if we can standardize the procedure and make it easier to perform, NPT will be applied more in clinical practice. In addition normal values among Asian ethnics are presented for appropriate interpretation of the test.

Keywords

  • Administration, Intranasal
  • Allergens/*diagnostic use
  • Animals
  • Asia
  • Humans
  • *Immunization
  • Immunologic Tests/methods/standards
  • *Population Groups
  • Predictive Value of Tests
  • Reference Standards
  • Rhinitis, Allergic, Perennial/*diagnosis/immunology/physiopathology
  • Rhinitis, Allergic, Seasonal/*diagnosis/immunology/physiopathology

UNIGE affiliation entities

Citation (ISO format)

TANTILIPIKORN, Pongsakorn, VICHYANOND, Pakit, LACROIX, Jean-Sylvain. Nasal provocation test: how to maximize its clinical use? In: Asian Pacific Journal of Allergy and Immunology, 2010, vol. 28, n° 4, p. 225–231.

Identifiers

Journal ISSN

0125-877X
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Technical informations

Creation

22/05/2012 15:15:43

First validation

22/05/2012 15:15:43

Update

14/03/2023 17:30:11

Status update

14/03/2023 17:30:11

Last indexation

29/10/2024 19:50:31
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