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Interictal arterial spin-labeling MRI perfusion in intractable epilepsy

Pendse, N.
Altrichter, S.
Viallon, M.
Federspiel, A.
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Published in Journal of Neuroradiology. 2010, vol. 37, no. 1, p. 60-63
Abstract INTRODUCTION: Magnetic resonance imaging (MRI) is required for the investigation of surgically intractable epilepsy. In addition to the standard MRI techniques, perfusion sequences can be added to improve visualization of underlying pathological changes. Arterial spin-labeling (ASL) MRI perfusion does not require contrast administration and, for this reason, may have advantages in these patients. METHODS: We report here on 16 patients with epilepsy who underwent MRI of the brain with ASL and positron emission tomography (PET). RESULTS: Despite a slightly reduced resolution with ASL, we found a correlation between ASL, PET and electrophysiological data, with hypoperfusion on ASL that corresponded with hypoperfusion on interictal PET. CONCLUSION: Given the correlation between ASL and PET and electrophysiology, perfusion with ASL could become part of the standard work-up in patients with epilepsy.
Keywords AdolescentAdultBrain/*pathologyChildEpilepsy/*diagnosisFemaleHumansMagnetic Resonance Angiography/*methodsMaleMiddle AgedReproducibility of ResultsSensitivity and SpecificitySpin LabelsYoung Adult
PMID: 19674791
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Research groups Epilepsie et Chirurgie (149)
Ischémie cérébrale et connectivité (801)
Groupe Schaller Karl Lothard (neurochirurgie) (851)
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PENDSE, N. et al. Interictal arterial spin-labeling MRI perfusion in intractable epilepsy. In: Journal of Neuroradiology, 2010, vol. 37, n° 1, p. 60-63. doi: 10.1016/j.neurad.2009.05.006 https://archive-ouverte.unige.ch/unige:20541

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Deposited on : 2012-05-22

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