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Hépatite D:oubliée mais pas disparue

Moradpour, Darius
Published in Revue médicale suisse. 2010, vol. 6, no. 261, p. 1656-1659
Abstract Hepatitis D virus (HDV) is a subviral agent which depends on the envelope proteins (HBsAg) of hepatitis B virus (HBV). Therefore, hepatitis D is observed only in patients infected with HBV. Chronic hepatitis D is the least frequent albeit most severe form of chronic viral hepatitis. A resurgence of chronic hepatitis D has been observed in Northern and Central Europe, mainly due to immigration of patients from regions with high prevalence. Every HBsAg-positive patient should be screened for concurrent HDV infection. Standard treatment consists of pegylated interferon-alpha for at least one year. Sustained virological response rates are approximately 20%. Liver transplantation should be considered in patients with advanced cirrhosis or limited hepatocellular carcinoma. Preventive measures for hepatitis D are the same as for hepatitis B.
Keywords Antiviral Agents/therapeutic useEuropean Union/statistics & numerical dataHepatitis B/complications*Hepatitis D/diagnosis/epidemiology/therapyHepatitis D, ChronicHepatitis Delta Virus/isolation & purificationHumansInterferon-alpha/therapeutic useLiver TransplantationPolyethylene Glycols/therapeutic usePrevalenceRecombinant ProteinsWorld Health
PMID: 20939399
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Research group Etudes et traitement de l'hépatite C et B (554)
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MORADPOUR, Darius, NEGRO, Francesco. Hépatite D:oubliée mais pas disparue. In: Revue médicale suisse, 2010, vol. 6, n° 261, p. 1656-1659. https://archive-ouverte.unige.ch/unige:20528

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Deposited on : 2012-05-22

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