Unsaturated fatty acids inhibit the expression of tumor suppressor phosphatase and tensin homolog (PTEN) via microRNA-21 up-regulation in hepatocytes
Contributeurs/tricesVinciguerra, Manlio; Sgroi, Antonino; Veyrat-Durebex, Christelle; Rubbia-Brandt, Laura; Buehler, Leo Hans; Foti, Michelangelo
Publié dansHepatology, vol. 49, no. 4, p. 1176-1184
Date de publication2009
Résumé
Mots-clés
- Animals
- Cell Line, Tumor
- Down-Regulation
- Epigenesis, Genetic
- Fatty Acids, Nonesterified/*metabolism
- Gene Expression Regulation
- Hepatocytes/*metabolism
- Humans
- MicroRNAs/*metabolism
- Oleic Acid/*metabolism
- PTEN Phosphohydrolase/*metabolism
- Promoter Regions, Genetic
- Protein Kinases/metabolism
- RNA, Messenger/metabolism
- Rats
- Rats, Wistar
- TOR Serine-Threonine Kinases
- Transcription Factor RelA/metabolism
- Up-Regulation
Structure d'affiliation
Citation (format ISO)
VINCIGUERRA, Manlio et al. Unsaturated fatty acids inhibit the expression of tumor suppressor phosphatase and tensin homolog (PTEN) via microRNA-21 up-regulation in hepatocytes. In: Hepatology, 2009, vol. 49, n° 4, p. 1176–1184. doi: 10.1002/hep.22737
Fichiers principaux (1)
Article
Identifiants
- PID : unige:20157
- DOI : 10.1002/hep.22737
- PMID : 19072831
ISSN du journal0270-9139