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The estimated number of patients with hepatocellular carcinoma selected for liver transplantation using expanded selection criteria
|Published in||Transplant International. 2009, vol. 22, no. 9, p. 869-875|
|Abstract||Recently, several groups have introduced expanded criteria for selection of patients with hepatocellular carcinoma (HCC) prior to transplant, but the exact number of potential newly recruited patients remains unclear. This registry-based study assessed 270 patients diagnosed with HCC. The potential number of transplant candidates was based on age ( ≤ 65 years), absence of metastases and macro-vascular invasion, and on 12 previously published, expanded selection criteria. A wide range of increase in the number of transplant candidates was observed (12-63% when compared with the number of such candidates who would have been selected solely based on the Milan criteria). The most conservative criteria were Seoul (Kwon, 2007; increase of 12%), Valencia (Silva, 2008; 16%), total tumor volume/alpha-fetoprotein (Toso, 2009; 20%) and UCSF (Yao, 2007; 20%). This data will assist Centers and policy agencies in predicting the need for resources linked to an expansion of criteria.|
|Keywords||Carcinoma, Hepatocellular/*therapy — Female — Humans — Liver Neoplasms/*therapy — Liver Transplantation/*methods — Male — Microcirculation — Middle Aged — Neoplasm Metastasis — Patient Selection — Preoperative Care — Registries — Time Factors — Waiting Lists|
|Research group||Transplantation et hépatologie (905)|
|TOSO, Christian et al. The estimated number of patients with hepatocellular carcinoma selected for liver transplantation using expanded selection criteria. In: Transplant International, 2009, vol. 22, n° 9, p. 869-875. doi: 10.1111/j.1432-2277.2009.00882.x https://archive-ouverte.unige.ch/unige:20131|