Scientific article

Impaired inhibition of proactive interference in abstinent individuals with alcoholism

Publication date2009

Cognitive impairment has been associated with higher risk of alcoholism and relapse. Recent theoretical refinements have separated inhibition of dominant response and inhibition of proactive interference. We assessed the latter using a directed-forgetting procedure in 38 recently detoxified individuals with alcoholism and in 26 controls. On this task, memory performance of letter trigrams was compared when presented alone, followed by a second trigram to be recalled, then a second trigram to be forgotten (directed-forgetting condition). Individuals with alcoholism recalled more letters to be forgotten and performed worse than controls in the directed-forgetting condition, which significantly correlated with the duration of alcoholism.

  • Adult
  • Alcoholism/*psychology/*rehabilitation
  • Attention
  • Female
  • Humans
  • Male
  • Memory Disorders/*etiology
  • Memory, Short-Term/*physiology
  • Middle Aged
  • Neuropsychological Tests
  • Pattern Recognition, Visual/physiology
  • Photic Stimulation/methods
  • *Proactive Inhibition
  • Reaction Time
  • Young Adult
Research group
Citation (ISO format)
NOEL, Xavier et al. Impaired inhibition of proactive interference in abstinent individuals with alcoholism. In: Neuropsychology, development, and cognition. Section A, Journal of clinical and experimental neuropsychology, 2009, vol. 31, n° 1, p. 57–64. doi: 10.1080/13803390801982726
Main files (1)
ISSN of the journal1380-3395

Technical informations

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