en
Scientific article
English

Visual analysis or semi-automated gray-scale-based color mapping of the carotid plaque: which method correlates the best with the presence of cerebrovascular symptoms and/or lesions on MRI?

Published inJournal of neuroimaging, vol. 19, no. 2, p. 119-126
Publication date2009
Abstract

BACKGROUND AND PURPOSE: To determine the correlation between carotid plaque morphology, assessed by two different ultrasonographic methods, and presence of cerebrovascular events and/or lesions on magnetic resonance imaging (MRI). PATIENTS AND METHODS: Visual analysis of plaque echogenicity using a five-type classification was performed. Further, a semi-automated gray-scale-based color mapping of the whole plaque and of its surface was achieved. RESULTS: There were 31 (35%) symptomatic (23 strokes and 8 transitory ischemic attacks [TIAs]) and 58 (65%) asymptomatic carotid stenoses. MRI lesions related to the carotid stenosis if located in the ipsilateral cortical, subcortical, or watershed area, were present in 27 cases (30%). In a multivariate logistic regression model, degree of stenosis (P= .03) and a predominant red color on the surface (P= .04) were independent factors associated with the presence of cerebrovascular events and/or lesions on MRI. Sensitivity and specificity were, respectively, 80% and 63% by combining degree of stenosis and color mapping of plaque surface. CONCLUSION: Degree of stenosis and a predominant red color on plaque surface were independent factors associated with the presence of cerebrovascular events and/or lesions on MRI. No correlation was observed with any particular type of plaque based on visual analysis alone.

Keywords
  • Aged
  • Brain/drug effects/*pathology
  • Carotid Arteries/*pathology
  • Carotid Stenosis/drug therapy/*pathology
  • Color
  • Coronary Disease/pathology
  • Female
  • Humans
  • Hypertension
  • Ischemic Attack, Transient/drug therapy/pathology
  • Logistic Models
  • Magnetic Resonance Imaging/*methods
  • Male
  • Multivariate Analysis
  • Observer Variation
  • Odds Ratio
  • ROC Curve
  • Sensitivity and Specificity
  • Stroke/drug therapy/pathology
Citation (ISO format)
MOMJIAN, Isabelle et al. Visual analysis or semi-automated gray-scale-based color mapping of the carotid plaque: which method correlates the best with the presence of cerebrovascular symptoms and/or lesions on MRI? In: Journal of neuroimaging, 2009, vol. 19, n° 2, p. 119–126. doi: 10.1111/j.1552-6569.2008.00268.x
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ISSN of the journal1051-2284
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