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Visual analysis or semi-automated gray-scale-based color mapping of the carotid plaque: which method correlates the best with the presence of cerebrovascular symptoms and/or lesions on MRI?
|Published in||Journal of neuroimaging. 2009, vol. 19, no. 2, p. 119-126|
|Abstract||BACKGROUND AND PURPOSE: To determine the correlation between carotid plaque morphology, assessed by two different ultrasonographic methods, and presence of cerebrovascular events and/or lesions on magnetic resonance imaging (MRI). PATIENTS AND METHODS: Visual analysis of plaque echogenicity using a five-type classification was performed. Further, a semi-automated gray-scale-based color mapping of the whole plaque and of its surface was achieved. RESULTS: There were 31 (35%) symptomatic (23 strokes and 8 transitory ischemic attacks [TIAs]) and 58 (65%) asymptomatic carotid stenoses. MRI lesions related to the carotid stenosis if located in the ipsilateral cortical, subcortical, or watershed area, were present in 27 cases (30%). In a multivariate logistic regression model, degree of stenosis (P= .03) and a predominant red color on the surface (P= .04) were independent factors associated with the presence of cerebrovascular events and/or lesions on MRI. Sensitivity and specificity were, respectively, 80% and 63% by combining degree of stenosis and color mapping of plaque surface. CONCLUSION: Degree of stenosis and a predominant red color on plaque surface were independent factors associated with the presence of cerebrovascular events and/or lesions on MRI. No correlation was observed with any particular type of plaque based on visual analysis alone.|
|Keywords||Aged — Brain/drug effects/*pathology — Carotid Arteries/*pathology — Carotid Stenosis/drug therapy/*pathology — Color — Coronary Disease/pathology — Female — Humans — Hypertension — Ischemic Attack, Transient/drug therapy/pathology — Logistic Models — Magnetic Resonance Imaging/*methods — Male — Multivariate Analysis — Observer Variation — Odds Ratio — ROC Curve — Sensitivity and Specificity — Stroke/drug therapy/pathology|
|Research group||Ischémie cérébrale et connectivité (801)|
|MOMJIAN, Isabelle et al. Visual analysis or semi-automated gray-scale-based color mapping of the carotid plaque: which method correlates the best with the presence of cerebrovascular symptoms and/or lesions on MRI?. In: Journal of neuroimaging, 2009, vol. 19, n° 2, p. 119-126. doi: 10.1111/j.1552-6569.2008.00268.x https://archive-ouverte.unige.ch/unige:19972|
Deposited on : 2012-04-23