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Title

Comparison of procalcitonin measurement by a semi-quantitative method and an ultra-sensitive quantitative method in a pediatric emergency department

Authors
Bailey, Benoit
Girodias, Jean-Bernard
Cousineau, Jocelyne
Delvin, Edgard
Published in Clinical Biochemistry. 2009, vol. 42, no. 15, p. 1557-1560
Abstract OBJECTIVE: To compare procalcitonin measurements between semi-quantitative and quantitative assays. METHOD: Procalcitonin was measured with the PCT-Q and the Kryptor assays in a pediatric emergency department. RESULTS: Among the 359 pairs of results, 103 had discordant results. The linear weighted kappa was 0.44 (95% CI 0.36, 0.51). The concordant/discordant results distribution varied depending on the laboratory technician (p=0.018). CONCLUSION: Agreement between procalcitonin measured semi-quantitatively and quantitatively was moderate. This is probably due to a subjective interpretation of the assay result.
Keywords Bacterial Infections/*blood/diagnosisBiological Assay/instrumentation/*methodsCalcitonin/*blood/diagnostic useChild, Preschool*Emergency Service, HospitalHumansInfantPediatrics/*methodsProspective StudiesProtein Precursors/*blood/diagnostic useRandomized Controlled Trials as TopicReproducibility of ResultsSensitivity and Specificity
Identifiers
PMID: 19615989
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Research group Etiologie des pneumonies et marqueurs inflammatoires chez l'enfant fébrile (183)
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MANZANO, Sergio et al. Comparison of procalcitonin measurement by a semi-quantitative method and an ultra-sensitive quantitative method in a pediatric emergency department. In: Clinical Biochemistry, 2009, vol. 42, n° 15, p. 1557-1560. https://archive-ouverte.unige.ch/unige:19941

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Deposited on : 2012-04-23

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