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Comparison of procalcitonin measurement by a semi-quantitative method and an ultra-sensitive quantitative method in a pediatric emergency department
|Published in||Clinical Biochemistry. 2009, vol. 42, no. 15, p. 1557-1560|
|Abstract||OBJECTIVE: To compare procalcitonin measurements between semi-quantitative and quantitative assays. METHOD: Procalcitonin was measured with the PCT-Q and the Kryptor assays in a pediatric emergency department. RESULTS: Among the 359 pairs of results, 103 had discordant results. The linear weighted kappa was 0.44 (95% CI 0.36, 0.51). The concordant/discordant results distribution varied depending on the laboratory technician (p=0.018). CONCLUSION: Agreement between procalcitonin measured semi-quantitatively and quantitatively was moderate. This is probably due to a subjective interpretation of the assay result.|
|Keywords||Bacterial Infections/*blood/diagnosis — Biological Assay/instrumentation/*methods — Calcitonin/*blood/diagnostic use — Child, Preschool — *Emergency Service, Hospital — Humans — Infant — Pediatrics/*methods — Prospective Studies — Protein Precursors/*blood/diagnostic use — Randomized Controlled Trials as Topic — Reproducibility of Results — Sensitivity and Specificity|
|Research group||Etiologie des pneumonies et marqueurs inflammatoires chez l'enfant fébrile (183)|
|MANZANO, Sergio et al. Comparison of procalcitonin measurement by a semi-quantitative method and an ultra-sensitive quantitative method in a pediatric emergency department. In: Clinical Biochemistry, 2009, vol. 42, n° 15, p. 1557-1560. https://archive-ouverte.unige.ch/unige:19941|