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Title

When once is not enough--further evidence of procalcitonin-guided antibiotic stewardship
Authors
Harbarth, Stéphan Juergen
Albrich, Werner C.
Muller, Beat
Published in Critical Care. 2009, vol. 13, no. 4, p. 165
Abstract Every day, critical care physicians around the world face the same challenge of the optimal timing of antimicrobial administration: when to start and when to stop antibiotics. Duration of antibiotic therapy for sepsis is mostly based on expert opinion, but its reduction is arguably the most promising approach to decrease emergence and selection of antibiotic resistance. The study by Hochreiter and colleagues presents another piece of evidence suggesting that procalcitonin may indeed be a valuable diagnostic parameter to guide antibiotic treatment duration, despite the ongoing controversy about the diagnostic accuracy of pro-calcitonin.
Keywords Anti-Bacterial Agents/administration & dosage/*therapeutic use — Calcitonin/*blood — Critical Illness — Decision Making — *Drug Administration Schedule — *Evidence-Based Medicine — Humans — Protein Precursors/*blood — Sepsis/drug therapy — Time Factors
Identifiers
PMID: 19664168
Full text
Article - public document Free access
Structures
Faculté de médecine / Section de médecine clinique / Département de médecine
Research group Groupe Harbarth Stephan (Staphylocoques dorés résistants à la méthicilline) (866)
Citation
(ISO format) 		HARBARTH, Stéphan Juergen, ALBRICH, Werner C., MULLER, Beat. When once is not enough--further evidence of procalcitonin-guided antibiotic stewardship. In: Critical Care, 2009, vol. 13, n° 4, p. 165. doi: 10.1186/cc7935 https://archive-ouverte.unige.ch/unige:19854

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Deposited on : 2012-04-23

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