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Title

Metabolic and cardiovascular responses during sub-maximal exercise in humans after 14 days of head-down tilt bed rest and inactivity

Authors
Capelli, C.
Antonutto, G.
Cautero, M.
Published in European Journal of Applied Physiology. 2008, vol. 104, no. 5, p. 909-18
Abstract VO(2), f (H), Q, SV, [Hb], C(a)O(2), QaO(2), MAP and R (P) were measured in 10 young subjects at rest and during exercise at 50, 100 and 150 W before and after 14 days of head-down tilt bed rest (HDTBR) and of ambulatory (AMB) control period. f (H) was 18 and 8% higher after HDTBR and AMB, respectively. SV dropped by 15% both after HDTBR and AMB, whereas Q did not change. After HDTBR, C(a)O(2) decreased at rest (-8%) and at 50 W (-5%), whereas QaO(2) did not change; MAP was 14 and 6% lower at rest and at 100 W and R (P) decreased by 23% only at rest. Changes in f (H) and SV were larger after HDTBR than after AMB. These results show that, notwithstanding the drop of SV, moderate-intensity dynamic exercise elicited a normal pressure response after 14 days of HDTBR.
Keywords AdultBed Rest/adverse effectsBlood PressureCardiac OutputCardiovascular DeconditioningExerciseHead-Down Tilt/adverse effectsHeart RateHemodynamicsHemoglobins/metabolismHumansMaleMuscle ContractionMuscle, Skeletal/blood supply/metabolismOxygen/bloodOxygen ConsumptionStroke VolumeTime FactorsWeightlessness Simulation/adverse effectsYoung Adult
Identifiers
PMID: 18716791
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Research group Métabolisme énergétique (642)
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CAPELLI, C. et al. Metabolic and cardiovascular responses during sub-maximal exercise in humans after 14 days of head-down tilt bed rest and inactivity. In: European Journal of Applied Physiology, 2008, vol. 104, n° 5, p. 909-18. https://archive-ouverte.unige.ch/unige:1980

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Deposited on : 2009-06-11

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