Assessing fracture risk and effects of osteoporosis drugs: bone mineral density and beyond

Davison, K Shawn; Kendler, David L.; Ammann, Patrick; Bauer, Douglas C.; Dempster, David W.; Dian, Larry; Hanley, David A.; Harris, Steven T.; McClung, Michael R.; Olszynski, Wojciech P.; Yuen, Chui K.

doi:10.1016/j.amjmed.2009.05.018

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Title		Assessing fracture risk and effects of osteoporosis drugs: bone mineral density and beyond
Authors		Davison, K Shawn Kendler, David L. Ammann, Patrick Bauer, Douglas C. Dempster, David W. Dian, Larry Hanley, David A. Harris, Steven T. McClung, Michael R. Olszynski, Wojciech P. Yuen, Chui K. show all authors [1 - 11]
Published in		American Journal of Medicine. 2009, vol. 122, no. 11, p. 992-997
Abstract		Although there have been numerous advances in the assessment of bone strength and fracture risk, the majority of these techniques can only be performed in research laboratories, making them largely unavailable to practicing clinicians. Prospective epidemiologic studies have identified risk factors that can be assessed within the clinic and combined with bone mineral density to allow clinicians to better identify untreated individuals at heightened risk for fracture and to make informed treatment decisions based on 10-year absolute fracture risk. This article discusses the assessment of fracture risk in clinical practice, reviews currently and soon-available bone measurement tools, and details the impacts of osteoporosis therapies on fracture risk.
Keywords		Absorptiometry, Photon — Bone Density — Bone Density Conservation Agents/therapeutic use — Fractures, Bone/etiology/prevention & control — Humans — Osteoporosis/complications/drug therapy/metabolism — Prognosis — *Risk Assessment — Risk Factors
Identifiers		DOI: 10.1016/j.amjmed.2009.05.018 PMID: 19854322
Full text		Article - Limited access to UNIGE
Structures		Faculté de médecine / Section de médecine clinique / Département de médecine Faculté de médecine / Section de médecine clinique / Département de réadaptation et gériatrie
Research group		Etudes précliniques de l'ostéoporose (606)
Citation (ISO format)		DAVISON, K Shawn et al. Assessing fracture risk and effects of osteoporosis drugs: bone mineral density and beyond. In: American Journal of Medicine, 2009, vol. 122, n° 11, p. 992-997. doi: 10.1016/j.amjmed.2009.05.018 https://archive-ouverte.unige.ch/unige:19759