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Title

Inter-informant agreement on diagnoses and prevalence estimates of anxiety disorders: direct interview versus family history method

Authors
Rougemont-Buecking, Ansgar
Jeanprêtre, Nicolas
Lustenberger, Yodok
Preisig, Martin
Published in Psychiatry Research. 2008, vol. 157, no. 1-3, p. 211-23
Abstract The aims of the present study were to: (1) assess agreement for diagnoses of specific anxiety disorders between direct interviews and the family history method; (2) compare prevalence estimates according to direct interviews and family history information; (3) test strategies to approximate prevalence estimates according to family history reports to those based on direct interviews; (4) test covariates of inter-informant agreement; and (5) test the likelihood of reporting disorders by informants. Analyses were based on family study data which included 1625 distinct informant (first-degree relatives and spouses)-index subject pairs. Our main findings were: (1) inter-informant agreement was satisfactory for panic disorder, agoraphobia, social phobia and obsessive-compulsive disorder; (2) the family history method provided lower prevalence estimates for all anxiety disorders (except for generalized anxiety disorder and obsessive-compulsive disorder) than direct interviews; (3) the lowering of diagnostic thresholds and the combination of multiple family history reports increased the accuracy of prevalence estimates according to the family history method; (4) female gender of index subjects was associated with poor agreement; and (5) informants, who themselves had a history of an anxiety disorder, were more likely to detect this disorder in their relatives which entails the risk of overestimation of the size of familial aggregation.
Keywords AdultAlgorithmsAnxiety Disorders/diagnosis/epidemiology/geneticsFemaleHumansMaleMedical History TakingMental Disorders/diagnosis/epidemiology/geneticsObserver VariationPrevalence
Identifiers
PMID: 17881063
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ROUGEMONT-BUECKING, Ansgar et al. Inter-informant agreement on diagnoses and prevalence estimates of anxiety disorders: direct interview versus family history method. In: Psychiatry Research, 2008, vol. 157, n° 1-3, p. 211-23. https://archive-ouverte.unige.ch/unige:1969

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Deposited on : 2009-06-11

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