Article - Limited access to UNIGE
Other version: http://www.mdconsult.com/das/article/body/323154182-2/jorg=journal%26source=%26sp=21972292%26sid=0/N/692038/s08898588...
Diagnosis and treatment of acquired aplastic anemia
|Published in||Hematology Oncology Clinics of North America. 2009, vol. 23, no. 2, p. 159-170|
|Abstract||Acquired severe aplastic anemia can be treated successfully with either immunosuppressive therapy or bone marrow transplantation. Although immunosuppressive therapy can be readily administered to all patients, it is not a curative approach and is associated with a higher risk of clonal evolution than is transplantation, which yields rapid and long-lasting hematologic remission. This article reviews the key diagnostic and prognostic factors that influence the choice of therapy in patients with acquired aplastic anemia.|
|Keywords||Age Factors — Anemia, Aplastic/*diagnosis/drug therapy/*therapy — Animals — Antilymphocyte Serum/*therapeutic use — Bone Marrow Transplantation/*immunology/mortality — Cyclosporine/*therapeutic use — Female — Fetal Blood/transplantation — Humans — Immunosuppressive Agents/*therapeutic use — Intercellular Signaling Peptides and Proteins/*therapeutic use — Male — Pregnancy — Prognosis|
|BACIGALUPO, Andrea, PASSWEG, Jakob. Diagnosis and treatment of acquired aplastic anemia. In: Hematology Oncology Clinics of North America, 2009, vol. 23, n° 2, p. 159-170. https://archive-ouverte.unige.ch/unige:19655|