A liposome-based mycobacterial vaccine induces potent adult and neonatal multifunctional T cells through the exquisite targeting of dendritic cells
Contributeurs/tricesKamath, Arun; Rochat, Anne-Françoise; Christensen, Dennis; Agger, Else Marie; Andersen, Peter; Lambert, Paul Henri; Siegrist, Claire-Anne
Publié dansPloS one, vol. 4, no. 6, e5771
Date de publication2009
Résumé
Mots-clés
- Adjuvants, Immunologic
- Animals
- Antigens, CD40/biosynthesis
- Antigens, CD86/biosynthesis
- CD4-Positive T-Lymphocytes/metabolism
- Cations
- Dendritic Cells/immunology/*metabolism
- Liposomes/*chemistry
- Lymph Nodes/pathology
- Mice
- Mice, Inbred C57BL
- Mycobacterium bovis/*immunology/metabolism
- T-Lymphocytes/immunology/*metabolism
- Tuberculosis Vaccines/*immunology
Groupe de recherche
Citation (format ISO)
KAMATH, Arun et al. A liposome-based mycobacterial vaccine induces potent adult and neonatal multifunctional T cells through the exquisite targeting of dendritic cells. In: PloS one, 2009, vol. 4, n° 6, p. e5771. doi: 10.1371/journal.pone.0005771
Fichiers principaux (1)
Article
Identifiants
- PID : unige:19544
- DOI : 10.1371/journal.pone.0005771
- PMID : 19492047
ISSN du journal1932-6203