Significant weight loss, achieved through bariatric surgery, anti-obesity pharmacological treatments, or intensive lifestyle modifications, is frequently associated with cutaneous and morphological sequelae leading to dermatological complications, functional limitations, and a significant psychosocial impact. Reconstructive plastic surgery (abdominoplasty/body lift, limb contouring, breast or cervicofacial procedures) improves comfort, body image, and quality of life, but it carries a risk of complications that requires careful patient selection, weight stabilization, and nutritional optimization. Access to care depends on medico-administrative criteria and documentation of functional limitations. Integration into multidisciplinary care pathways aims to ensure efficient and equitable management.