Targeting ferritinophagy to iron out <i>Tet2</i>-mutant cells

Larrue, Clément; Tamburini Bonnefoy, Jérôme

doi:10.1182/blood.2025029890

Scientific article

Editorial

English

Targeting ferritinophagy to iron out Tet2-mutant cells

ContributorsLarrue, Clément

; Tamburini Bonnefoy, Jérôme

Published inBlood, vol. 146, no. 10, p. 1146-1148

Publication date2025-09-04

Abstract

Comment on : Loke J, Kim PG, Nguyen TTP, Boileau M, McConkey M, Miller A, Shin W, Hergott CB, Ericsson M, Nordstrom A, Llopis PM, Armstrong SA, Mancias JD, Ebert BL. An in vivo barcoded CRISPR-Cas9 screen identifies Ncoa4-mediated ferritinophagy as a dependence in Tet2-deficient hematopoiesis. Blood. 2025 Sep 4;146(10):1174-1186. doi: 10.1182/blood.2024028033. PMID: 40493884; PMCID: PMC12783511.

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de médecine

Research groups

Lymphomes et leucémies (994)

Citation (ISO format)

LARRUE, Clément, TAMBURINI BONNEFOY, Jérôme. Targeting ferritinophagy to iron out Tet2-mutant cells. In: Blood, 2025, vol. 146, n° 10, p. 1146–1148. doi: 10.1182/blood.2025029890

Article (Published version)

Identifiers

PID : unige:194542
DOI : 10.1182/blood.2025029890
PMID : 40906503

Additional URL for this publicationhttps://ashpublications.org/blood/article/146/10/1146/547030/Targeting-ferritinophagy-to-iron-out-Tet2-mutant

Journal ISSN0006-4971

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Targeting ferritinophagy to iron out Tet2-mutant cells

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