PGE<sub>2</sub> inhibition to prevent AML escape from NK cells

Simonetta, Federico

doi:10.1182/blood.2024027931

Scientific article

Editorial

English

PGE₂ inhibition to prevent AML escape from NK cells

ContributorsSimonetta, Federico

Published inBlood, vol. 145, no. 13, p. 1338-1339

Publication date2025-03-27

Abstract

Comment on : Rothfuß C, Baumann T, Donakonda S, Brauchle B, Marcinek A, Urban C, Mergner J, Pedde AM, Hirschberger A, Krupka C, Neumann AS, Hänel G, Merten C, Öllinger R, Hecker JS, Bauer T, Schmid C, Götze KS, Altomonte J, Bücklein V, Jacobs R, Rad R, Dawid C, Simeoni L, Schraven B, Pichlmair A, Subklewe M, Knolle PA, Böttcher JP, Höchst B. Two-layered immune escape in AML is overcome by Fcγ receptor activation and inhibition of PGE2 signaling in NK cells. Blood. 2025 Mar 27;145(13):1395-1406. doi: 10.1182/blood.2024025706. PMID: 39840945.

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de médecine

Research groups

Thérapie cellulaire et transplantation (1054)

Citation (ISO format)

SIMONETTA, Federico. PGE₂ inhibition to prevent AML escape from NK cells. In: Blood, 2025, vol. 145, n° 13, p. 1338–1339. doi: 10.1182/blood.2024027931

Article (Published version)

Identifiers

PID : unige:194540
DOI : 10.1182/blood.2024027931
PMID : 40146159

Additional URL for this publicationhttps://ashpublications.org/blood/article/145/13/1338/536233/PGE2-inhibition-to-prevent-AML-escape-from-NK

Journal ISSN0006-4971

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PGE2 inhibition to prevent AML escape from NK cells

Technical informations

PGE₂ inhibition to prevent AML escape from NK cells