Objective: To assess the prevalence of burnout among United States (US) uveitis specialists, identify contributing factors and propose interventions to reduce risk of burnout.

Design: Cross-sectional Survey PARTICIPANTS: Uveitis specialists practicing in the United States METHODS: A survey including questions on respondent demographics, practice patterns, practice infrastructure as well as a validated tool to measure physician burnout (mini Z 2.0 survey) was sent to the American Uveitis Society (AUS) and Young Uveitis Society (YUS) listservs. Multiple logistic regression models using demographic variables and practice specifics as covariates were used to assess risk factors for burnout.

Main outcome measures: Proportion at risk for burnout (mini Z score <40), self-reported metrics of burnout and contributing factors.

Results: Ninety-five uveitis specialists completed the survey (response rate 43.8%). All respondents dedicated at least 40% of their clinical time towards uveitis patients. Of those practicing an additional ophthalmic subspecialty (including comprehensive ophthalmology), 81% felt uveitis was more stressful than their other subspecialty. Overall, 41% reported varying degrees of burnout. The median mini Z score was 30 with only 9.5% having a score ≥40. Being in a university-based practice (p=0.045), feelings of inadequate compensation (p=0.002), a regional shortage of uveitis specialists (p=0.005) and inadequate support staff (p<0.00001) were associated with lower mini Z scores. Mini Z scores did not vary significantly when responses were stratified based on respondent age, years in practice, gender, or whether immunosuppression was independently managed.

Conclusions: Burnout was reported in 41% of surveyed uveitis specialists with another 49.5% at risk for burnout. Practice-level variables such as adequacy of support staff, perceived adequacy of compensation, practice setting as well as workforce shortages impacted burnout risk.