As in previous years, 2025 was marked by significant scientific progress. This article focuses on three current topics in emergency medicine. First, it reviews the available evidence on vascular access during cardiac arrest and highlights that intra-osseous access is not superior to peripheral venous access. Second, it summarizes recent advances in trauma management, including the prognostic value of sternal capillary refill time in polytrauma patients, as well as the benefits of maintaining a transfusion target of 90 g/l in patients with brain injury. Finally, this article underscores the current limitations of thrombectomy for distal vessel strokes and discusses its promising perspectives in the treatment of pulmonary embolism.