New data on geology, metamorphism, mineralogy and formation mechanisms of the scheelite-skarn of Salanfe are presented. The skarn, situated in a metasedimentary sequence of possible Pre-Cambrian age in the Aiguilles Rouges massif (Swiss Alps), was formed during a Late Variscan high temperature metamorphic event. Skarn mineralogy shows a typical evolution from a metamorphic stage to ore skarn stages (prograde and retrograde). In the retrograde stage of the ore skarn, pyroxene is replaced by hydrated minerals (chlorite, epidote, amphibole) or by the association hematite-calcite-quartz depending on the distance from the marble. The main ore minerals are scheelite, arsenopyrite and gold