Scientific article
French

Sarcoïdose osseuse : une manifestation sous-reconnue d’une maladie multisystémique

Other titleBone sarcoidosis: an underrecognized manifestation of a multisystemic disease
Published inRevue médicale suisse, vol. 22, no. 956, p. 1-5
Publication date2026-04-01
First online date2026-04-01
Abstract

Bone sarcoidosis is a rare manifestation, reported in 1-15% of patients, and most often presenting as a multisystemic disease. Although it was historically described as predominantly affecting the phalanges (Perthes-Jüngling disease), axial involvement (spine, pelvis) is now recognized as frequent, most likely due to the increased use of MRI and PET-CT scans. This condition is often asymptomatic and discovered incidentally, but it can cause pain and disabling complications. Lesions can appear lytic, sclerotic, or mixed, with no specific radiological pattern. Definitive diagnosis relies on a bone or bone marrow biopsy demonstrating non-caseating granulomas and ruling out infection or malignancy. Treatment is not standardized and mainly relies on systemic glucocorticoids, with immunosuppressive agents added when necessary.

Keywords
  • Humans
  • Sarcoidosis / diagnosis
  • Sarcoidosis / pathology
  • Sarcoidosis / drug therapy
  • Sarcoidosis / therapy
  • Bone Diseases / diagnosis
  • Bone Diseases / pathology
  • Bone Diseases / drug therapy
  • Glucocorticoids / therapeutic use
  • Glucocorticoids / administration & dosage
  • Magnetic Resonance Imaging / methods
  • Immunosuppressive Agents / therapeutic use
  • Positron Emission Tomography Computed Tomography / methods
  • Biopsy
  • Diagnosis, Differential
Citation (ISO format)
BENIADA, Camille et al. Sarcoïdose osseuse : une manifestation sous-reconnue d’une maladie multisystémique. In: Revue médicale suisse, 2026, vol. 22, n° 956, p. 1–5. doi: 10.53738/REVMED.2026.22.956.e48520
Main files (1)
Article (Published version)
accessLevelRestrictedaccessLevelPublic 02/10/2027
Identifiers
Journal ISSN1660-9379
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