Os centrale carpi is an uncommon accessory carpal bone. We report, to the best of our knowledge, the first case of imaging findings of "os centrale carpi bone bruising" simulating an acute scaphoid fracture. The various differential diagnoses of this entity are discussed. A 22-year-old man presented to our hospital with dorsolateral wrist pain following trauma. Radiography revealed a potential fracture line in the distal pole of the scaphoid and a fracture of the base of the ulnar styloid. Magnetic resonance imaging (MRI) revealed bone bruising of the os centrale carpi and a fracture of the ulnar styloid process. The objective of this case report is to present the imaging findings of os centrale carpi bone bruising, an uncommon occurrence in wrist trauma.