Scientific article

Epidemiology of pulmonary hypertension: new data from the Swiss registry

Published inSchweizerische medizinische Wochenschrift, vol. 138, no. 25-26, p. 379-384
Publication date2008

BACKGROUND: since 1999 data from pulmonary hypertension (PH) patients from all PH centres in Switzerland were prospectively collected. We analyse the epidemiological aspects of these data. METHODS: PH was defined as a mean pulmonary artery pressure of >25 mm Hg at rest or >30 mm Hg during exercise. Patients with pulmonary arterial hypertension (PAH), PH associated with lung diseases, PH due to chronic thrombotic and/or embolic disease (CTEPH), or PH due to miscellaneous disorders were registered. Data from adult patients included between January 1999 and December 2004 were analysed. RESULTS: 250 patients were registered (age 58 +/- 16 years, 104 (41%) males). 152 patients (61%) had PAH, 73 (29%) had CTEPH and 18 (7%) had PH associated with lung disease. Patients <50 years (32%) were more likely to have PAH than patients >50 years (76% vs. 53%, p <0.005). Twenty-four patients (10%) were lost to followup, 58 patients (26%) died and 150 (66%) survived without transplantation or thrombendarterectomy. Survivors differed from patients who died in the baseline six-minute walking distance (400 m [300-459] vs. 273 m [174-415]), the functional impairment (NYHA class III/IV 86% vs. 98%), mixed venous saturation (63% [57-68] vs. 56% [50-61]) and right atrial pressure (7 mm Hg [4-11] vs. 11 mm Hg [4-18]). DISCUSSION: PH is a disease affecting adults of all ages. The management of these patients in specialised centres guarantees a high quality of care. Analysis of the registry data could be an instrument for quality control and might help identify weak points in assessment and treatment of these patients.

  • Adult
  • Female
  • Humans
  • Hypertension, Pulmonary/*epidemiology/physiopathology
  • Male
  • Middle Aged
  • Morbidity/trends
  • Prospective Studies
  • Pulmonary Wedge Pressure/physiology
  • Registries/*statistics & numerical data
  • Severity of Illness Index
  • Survival Rate/trends
  • Switzerland/epidemiology
Citation (ISO format)
TUELLER, Claudia et al. Epidemiology of pulmonary hypertension: new data from the Swiss registry. In: Schweizerische medizinische Wochenschrift, 2008, vol. 138, n° 25-26, p. 379–384. doi: 10.4414/smw.2008.11915
Updates (1)
ISSN of the journal0036-7672

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