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unige:19220 
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Epidemiology of pulmonary hypertension: new data from the Swiss registry |
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| Published in | Swiss Medical Weekly. 2008, vol. 138, no. 25-26, p. 379-384 | |
| Abstract | BACKGROUND: since 1999 data from pulmonary hypertension (PH) patients from all PH centres in Switzerland were prospectively collected. We analyse the epidemiological aspects of these data. METHODS: PH was defined as a mean pulmonary artery pressure of >25 mm Hg at rest or >30 mm Hg during exercise. Patients with pulmonary arterial hypertension (PAH), PH associated with lung diseases, PH due to chronic thrombotic and/or embolic disease (CTEPH), or PH due to miscellaneous disorders were registered. Data from adult patients included between January 1999 and December 2004 were analysed. RESULTS: 250 patients were registered (age 58 +/- 16 years, 104 (41%) males). 152 patients (61%) had PAH, 73 (29%) had CTEPH and 18 (7%) had PH associated with lung disease. Patients <50 years (32%) were more likely to have PAH than patients >50 years (76% vs. 53%, p <0.005). Twenty-four patients (10%) were lost to followup, 58 patients (26%) died and 150 (66%) survived without transplantation or thrombendarterectomy. Survivors differed from patients who died in the baseline six-minute walking distance (400 m [300-459] vs. 273 m [174-415]), the functional impairment (NYHA class III/IV 86% vs. 98%), mixed venous saturation (63% [57-68] vs. 56% [50-61]) and right atrial pressure (7 mm Hg [4-11] vs. 11 mm Hg [4-18]). DISCUSSION: PH is a disease affecting adults of all ages. The management of these patients in specialised centres guarantees a high quality of care. Analysis of the registry data could be an instrument for quality control and might help identify weak points in assessment and treatment of these patients. | |
| Keywords | Adult — Female — Humans — Hypertension, Pulmonary/*epidemiology/physiopathology — Male — Middle Aged — Morbidity/trends — Prospective Studies — Pulmonary Wedge Pressure/physiology — Registries/*statistics & numerical data — Severity of Illness Index — Survival Rate/trends — Switzerland/epidemiology | |
| Identifiers | PMID: 18587690 | |
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| Citation (ISO format) | TUELLER, Claudia et al. Epidemiology of pulmonary hypertension: new data from the Swiss registry. In: Swiss Medical Weekly, 2008, vol. 138, n° 25-26, p. 379-384. https://archive-ouverte.unige.ch/unige:19220 |
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