Scientific article
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English

Structural and regulatory principles underlying apicomplexan conoid function

First online date2026-02-06
Abstract

Zeng et al. and Qian et al. reveal in their cryogenic electron microscopy (cryo-EM) studies how apicomplexan parasites extensively remodel tubulin to construct the conoid, a specialized invasion organelle. Distinct microtubule assemblies integrate mechanical support, force generation, and secretion control, providing a structural framework that underpins parasite motility and host cell entry.

Keywords
  • Toxoplasma gondii
  • Conoid fibers
  • Invasion
  • Microtubules
  • Motility
  • Preconoidal rings
Citation (ISO format)
TELL I PUIG, Albert, SOLDATI-FAVRE, Dominique. Structural and regulatory principles underlying apicomplexan conoid function. In: Trends in parasitology, 2026. doi: 10.1016/j.pt.2026.01.002
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Article (Published version)
Identifiers
Journal ISSN1471-4922
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30downloads

Technical informations

Creation08/02/2026 01:33:57
First validation10/02/2026 14:40:27
Update10/02/2026 14:40:27
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