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Plasmodium falciparum Malaria and Atovaquone-Proguanil Treatment Failure

ContributorsDurand, Rémy; Prendki, Virginieorcid; Cailhol, Johann; Hubert, Véronique; Ralaimazava, Pascal; Massias, Laurent; Bouchaud, Olivier; Le Bras, Jacques
Published inEmerging infectious diseases, vol. 14, no. 2, p. 320-322
Publication date2008-02
First online date2008-02
Abstract

We noticed overrepresentation of atovaquone-proguanil therapeutic failures among Plasmodium falciparum-infected travelers weighing >100 kg. We report here 1 of these cases, which was not due to resistant parasites or impaired drug bioavailability. The follow-up of such patients should be strengthened.

Keywords
  • Adult
  • Animals
  • Antimalarials / administration & dosage
  • Antimalarials / therapeutic use
  • Atovaquone / administration & dosage
  • Atovaquone / therapeutic use
  • Drug Therapy, Combination
  • Humans
  • Malaria, Falciparum / drug therapy
  • Malaria, Falciparum / parasitology
  • Male
  • Plasmodium falciparum / drug effects
  • Proguanil / administration & dosage
  • Proguanil / therapeutic use
  • Treatment Failure
Affiliation entities Not a UNIGE publication
Research groups
Citation (ISO format)
DURAND, Rémy et al. Plasmodium falciparum Malaria and Atovaquone-Proguanil Treatment Failure. In: Emerging infectious diseases, 2008, vol. 14, n° 2, p. 320–322. doi: 10.3201/eid1402.070945
Main files (1)
Article (Published version)
accessLevelPublic CC0
Identifiers
Additional URL for this publicationhttp://wwwnc.cdc.gov/eid/article/14/2/07-0945_article.htm
Journal ISSN1080-6040
9views
55downloads

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