Antibiotic use and good practice in 314 French hospitals : The 2010 SPA2 prevalence study

Alfandari, S; Robert, J; Péan, Y; Rabaud, C; Bedos, J P; Varon, E; Lepape, A; Bru, J P; Gauzit, R; French Infectious Diseases Society (SPILF); French National Observatory for Epidemiology of Bacterial Resistance to Antibiotics (ONERBA); SPA2 group

doi:10.1016/j.medmal.2015.10.001

Scientific article

English

Antibiotic use and good practice in 314 French hospitals : The 2010 SPA2 prevalence study

Other titleEnquête SPA2 de prévalence et de bon usage des anti-infectieux dans 314 hôpitaux français en 2010

ContributorsAlfandari, S; Robert, J; Péan, Y; Rabaud, C; Bedos, J P; Varon, E; Lepape, A; Bru, J P; Gauzit, R; French Infectious Diseases Society (SPILF); French National Observatory for Epidemiology of Bacterial Resistance to Antibiotics (ONERBA); SPA2 group

CollaboratorsPrendki, Virginie

Published inMédecine et maladies infectieuses, vol. 45, no. 11-12, p. 475-480

Publication date2015

First online date2015-11-21

Abstract

Objectives: We aimed to assess antibiotic prescriptions to identify potential targets for improvement.

Methods: We conducted a point prevalence survey (November 2010) of antibiotic use in 314 voluntary hospitals recruited by the French Infectious Diseases Society (SPILF) and the National Observatory for Epidemiology of Bacterial Resistance to Antimicrobials (ONERBA). Data were entered online, immediately analyzed and exported.

Results: The prevalence of antibiotic use was 19.5% (9059/46,446patients). A higher prevalence was observed in the infectious disease (58.4%), hematology (58%), and intensive care (48.7%) units. The three most frequently used antibiotic classes were aminopenicillins (23.8%), fluoroquinolones (17.9%), and 3rd-generation cephalosporins (16.7%). A monotherapy was prescribed to 64% of patients. The reasons for the antibiotic prescription were written in the medical records of 74% of patients and 62% were consistent with the local guidelines.

Conclusion: Our results are similar to that of other studies. Various local targets for improvement have been identified to help hospitals define a better antibiotic stewardship.

Keywords

Antibiotic stewardship
Antibiotics
Antibiotique
Audit
Bon usage
Anti-Bacterial Agents / therapeutic use
Cross-Sectional Studies
Drug Utilization / standards
Drug Utilization / statistics & numerical data
Female
France
Hospitals
Humans
Male
Middle Aged

Affiliation entities

Not a UNIGE publication

Research groups

Infections de la personne âgée (1062)

Citation (ISO format)

ALFANDARI, S et al. Antibiotic use and good practice in 314 French hospitals : The 2010 SPA2 prevalence study. In: Médecine et maladies infectieuses, 2015, vol. 45, n° 11-12, p. 475–480. doi: 10.1016/j.medmal.2015.10.001