Rapid childhood T-ALL growth in xenograft models correlates with mature phenotype and NF-κB pathway activation but not with poor prognosis
Published inLeukemia, vol. 29, no. 4, p. 977-980
Publication date2015-04
First online date2014-11-05
Keywords
- Adolescent
- Animals
- Antineoplastic Agents / pharmacology
- Apoptosis / drug effects
- Cell Cycle / drug effects
- Child
- Coculture Techniques
- Gene Expression Regulation, Neoplastic
- Graft Survival
- Humans
- Mice
- Mice, SCID
- NF-kappa B / antagonists & inhibitors
- NF-kappa B / genetics
- NF-kappa B / metabolism
- Nitriles / pharmacology
- Oncogene Proteins, Fusion / genetics
- Oncogene Proteins, Fusion / metabolism
- Phenotype
- Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / genetics
- Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / metabolism
- Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / pathology
- Prognosis
- Signal Transduction
- Stromal Cells / cytology
- Stromal Cells / metabolism
- Sulfones / pharmacology
- T-Lymphocytes / metabolism
- T-Lymphocytes / pathology
- Transplantation, Heterologous
- Xenograft Model Antitumor Assays
- Young Adult
Affiliation entities Not a UNIGE publication
Research groups
Citation (ISO format)
POGLIO, S et al. Rapid childhood T-ALL growth in xenograft models correlates with mature phenotype and NF-κB pathway activation but not with poor prognosis. In: Leukemia, 2015, vol. 29, n° 4, p. 977–980. doi: 10.1038/leu.2014.317
Main files (1)
Article (Published version)
Identifiers
- PID : unige:188778
- DOI : 10.1038/leu.2014.317
- PMID : 25371179
Additional URL for this publicationhttps://www.nature.com/articles/leu2014317
Journal ISSN0887-6924
