Scientific article
OA Policy
English

Description and validation of the Postoperative Discharge Recovery State outcome : a patient-partnered population-based cohort study

CollaboratorsBoet, Sylvainorcid
First online date2025-07-25
Abstract

Background: Older adults prioritise independent return home after surgery. Most discharge outcomes are binary composites that do not incorporate temporal information. We defined and validated a novel ordinal outcome, the Postoperative Discharge Recovery State, and prioritised its temporal measurement, to overcome these limitations.

Methods: This retrospective cohort study was conducted with patient partnership. Adults ≥65 yr having major, elective, noncardiac, non-orthopaedic surgery were identified from 2012 to 2022 using linked, routinely collected data in Ontario, Canada. Construct, convergent, and predictive validity were estimated. A multivariable ordinal regression model was derived and internally-externally validated.

Results: We included 84 422 older adult surgical patients. At the patient-prioritised postoperative day 90, the distribution of patients across Postoperative Discharge Recovery State categories was: (1) dead (2718; 3.2%); (2) hospitalised (1696; 2.0%); (3) in long-term care (179; 0.2%); (4) in rehabilitation (593; 0.7%); and (5) at home (79 236; 93.9%). Directionally expected associations with baseline characteristics supported construct validity. Consistency in associations over time supported reliability. Relationships with days alive and at home supported convergent (ρ=0.373) and predictive (fewer days at home with worse recovery state) validity. A prespecified ordinal logistic regression model had inadequate accuracy (c-statistic 0.700, poor calibration) to support its clinical use.

Conclusions: The Postoperative Discharge Recovery State is a 5-level ordinal outcome that can be applied at key time points after surgery to quantify the proportion of patients in patient-prioritised discharge locations. Validity and reliability support utility, but further development will be required to maximise information gain relative to binary outcomes.

Keywords
  • Epidemiology
  • Geriatrics
  • Patient-oriented research
  • Surgery
  • Validation
Affiliation entities Not a UNIGE publication
Funding
  • Institute for Clinical Evaluative Sciences
  • Canadian Institutes of Health Research
Citation (ISO format)
HLADKOWICZ, Emily et al. Description and validation of the Postoperative Discharge Recovery State outcome : a patient-partnered population-based cohort study. In: British journal of anaesthesia, 2025. doi: 10.1016/j.bja.2025.05.020
Main files (1)
Article (Published version)
Identifiers
Journal ISSN0007-0912
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170downloads

Technical informations

Creation26/07/2025 12:38:27
First validation12/08/2025 07:00:27
Update12/08/2025 07:00:27
Status update12/08/2025 07:00:27
Last indexation12/08/2025 07:00:28
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