Reply to : Biebelberg B. Shorter antibiotic courses for bloodstream infections can reduce healthcare spending. Intensive Care Med. 2025 Jun 4. doi: 10.1007/s00134-025-07952-8. Epub ahead of print. PMID: 40464903. Which is a comment on : Gajdos L, Buetti N, Tabah A, Ruckly S, Akova M, Sjöval F, Arvanti K, de Waele J, Bracht H, Barbier F, Timsit JF; EUROBACT-2 Study Group, the European Society of Intensive Care Medicine (ESICM), the European Society of Clinical Microbiology, the Infectious Diseases (ESCMID) Study Group for Infections in Critically Ill Patients (ESGCIP) and the OUTCOMEREA Network. Shortening antibiotic therapy duration for hospital-acquired bloodstream infections in critically ill patients: a causal inference model from the international EUROBACT-2 database. Intensive Care Med. 2025 Mar;51(3):518-528. doi: 10.1007/s00134-025-07857-6. Epub 2025 Apr 7. PMID: 40192823. https://archive-ouverte.unige.ch/unige:185050