• Home
  1. Home
  2. Rethinking jaundice : A buildup of unconjugated bilirubin may be a protective response to malaria
Scientific article
Comment
English

Rethinking jaundice : A buildup of unconjugated bilirubin may be a protective response to malaria

ContributorsKloehn, Joachim; Soldati-Favre, Dominiqueorcid
Published inScience, vol. 388, no. 6752, p. 1132-1133
First online date2025-06-12
Abstract

A buildup of unconjugated bilirubin may be a protective response to malaria.

Comment on : Figueiredo A, Rastogi ST, Ramos S, Nogueira F, De Villiers K, de Sousa AGG, Votborg-Novél L, von Wedel C, Tober-Lau P, Jentho E, Pagnotta S, Mesquita M, Cardoso S, Bortolussi G, Muro AF, Tranfield EM, Thibaud J, Duarte D, Sousa AL, Pinto SN, Kitoko J, Mombo-Ngoma G, Mischlinger J, Junttila S, Alenquer M, Amorim MJ, Vasavda C, Bosma PJ, Violante S, Drotleff B, Paixão T, Portugal S, Kurth F, Elo LL, Paul BD, Martins R, Soares MP. A metabolite-based resistance mechanism against malaria. Science. 2025 Jun 12;388(6752):eadq6741. doi: 10.1126/science.adq6741. Epub 2025 Jun 12. PMID: 40504905.

Keywords
  • Bilirubin / blood
  • Bilirubin / metabolism
  • Humans
  • Jaundice / etiology
  • Malaria, Falciparum / complications
  • Plasmodium falciparum / growth & development
Affiliation entities
Research groups
Citation (ISO format)
KLOEHN, Joachim, SOLDATI-FAVRE, Dominique. Rethinking jaundice : A buildup of unconjugated bilirubin may be a protective response to malaria. In: Science, 2025, vol. 388, n° 6752, p. 1132–1133. doi: 10.1126/science.ady7161
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
Additional URL for this publicationhttps://www.science.org/doi/10.1126/science.ady7161
Journal ISSN0036-8075
139views
0downloads

Technical informations

Creation15/06/2025 08:01:59
First validation16/06/2025 07:18:53
Update16/06/2025 07:18:53
Status update16/06/2025 07:18:53
Last indexation16/06/2025 07:18:54
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack