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Two-in-one: bifunctional regulators synchronizing developmental events in bacteria

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Published in Trends in Cell Biology. 2012, vol. 22, no. 1, p. 14-21
Abstract Developmental events are executed with delicate precision and are strictly in tune with one another. Whereas synchronization is generally attained at the transcriptional level via DNA-binding proteins that regulate multiple genetic modules, numerous recent studies using bacterial model systems reveal that bifunctional proteins are often appropriated as molecular couplers that act at the post-translational level. Here, we detail the developmental events that underlie such coupling and recap the molecular mechanisms by which coupling is achieved.
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PMID: 22014899
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RADHAKRISHNAN, Sunish Kumar, VIOLLIER, Patrick. Two-in-one: bifunctional regulators synchronizing developmental events in bacteria. In: Trends in Cell Biology, 2012, vol. 22, n° 1, p. 14-21. https://archive-ouverte.unige.ch/unige:18384

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Deposited on : 2012-02-14

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