Cardiogenic shock (CS) is highly prevalent in the intensive care unit (ICU) and is characterized by a 7 decreased cardiac output associated with impairment in splanchnic territory perfusion. It may be 8 secondary to a heart disease or may develop as a part of a shock syndrome. As patients suffering 9 from chronic heart failure are at high risk of undernutrition and lean tissue losses, early optimal 10 nutritional support could be a key point of the management of CS patients. Early enteral nutrition 11 (EN) is usually recommended in the ICU. However, as the use of EN increases mesenteric arterial 12 output, EN could increase the risk of mesenteric ischemia and sepsis in CS patients. Simultaneously, 13 parenteral nutrition (PN) administration is associated with a reduction in mesenteric arterial output 14 that could prevent ischemia in the liver and intestine. Therefore, current guidelines recommend to Q2 15 not beginning EN before the hemodynamic status is stabilized and to infuse EN at a low rate within 16 the 72 h following CS. PN must not be begun in the 48 h following ICU admission. From day 4 to 17 day 8 after admission, if EN could not be increased because of gastrointestinal intolerance, 18 supplemental PN could prevent energy deficit and reduce the proportion of patients with nosocomial 19 infections, the number of antibiotics days, and the duration of mechanical ventilation. Such a 20 nutritional strategy could prevent from intestinal failure related to insufficient splanchnic perfusion 21 and may improve the clinical outcome of patients with CS. These hypotheses have to be verified in 22 CS patients in a specific clinical trial.