Scientific article
OA Policy
English

Sensitivity of contact-tracing for COVID-19 in Thailand: a capture-recapture application

Published inBMC infectious diseases, vol. 22, no. 1, 101
Publication date2022-01-29
First online date2022-01-29
Abstract

Background: We investigate the completeness of contact tracing for COVID-19 during the first wave of the COVID-19 pandemic in Thailand, from early January 2020 to 30 June 2020.

Methods: Uni-list capture-recapture models were applied to the frequency distributions of index cases to inform two questions: (1) the unobserved number of index cases with contacts, and (2) the unobserved number of index cases with secondary cases among their contacts.

Results: Generalized linear models (using Poisson and logistic families) did not return any significant predictor (age, sex, nationality, number of contacts per case) on the risk of transmission and hence capture-recapture models did not adjust for observed heterogeneity. Best fitting models, a zero truncated negative binomial for question 1 and zero-truncated Poisson for question 2, returned sensitivity estimates for contact tracing performance of 77.6% (95% CI = 73.75-81.54%) and 67.6% (95% CI = 53.84-81.38%), respectively. A zero-inflated negative binomial model on the distribution of index cases with secondary cases allowed the estimation of the effective reproduction number at 0.14 (95% CI = 0.09-0.22), and the overdispersion parameter at 0.1.

Conclusion: Completeness of COVID-19 contact tracing in Thailand during the first wave appeared moderate, with around 67% of infectious transmission chains detected. Overdispersion was present suggesting that most of the index cases did not result in infectious transmission chains and the majority of transmission events stemmed from a small proportion of index cases.

Keywords
  • COVID-19
  • Capture-recapture
  • Contact tracing
  • Sensitivity
  • Thailand
  • Contact Tracing
  • Humans
  • Pandemics
  • SARS-CoV-2
  • Thailand / epidemiology
Affiliation entities Not a UNIGE publication
Citation (ISO format)
LERDSUWANSRI, R. et al. Sensitivity of contact-tracing for COVID-19 in Thailand: a capture-recapture application. In: BMC infectious diseases, 2022, vol. 22, n° 1, p. 101. doi: 10.1186/s12879-022-07046-6
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Article (Published version)
Identifiers
Journal ISSN1471-2334
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