Scientific article

Open access

English

Hepatitis E Virus Infection Epidemiology in Recipients of Allogeneic Hematopoietic Cell Transplant

ContributorsCourjon, Johan

; Portillo, Vera

; Yerly Ferrillo, Sabine; Vetter, Pauline

; Schibler, Manuel; Mappoura, Maria; Morin, Sarah; Giannotti, Federica; Mamez, Anne-Claire; Van Delden, Christian; Kaiser, Laurent; Chalandon, Yves

; Masouridi Levrat, Stavroula; Neofytos, Dionysios

Published inOpen forum infectious diseases, vol. 10, no. 12, ofad595

Publication date2023-12

First online date2023-11-24

Abstract

Among 292 recipients of allogeneic hematopoietic cell transplant (2018-2022), 64 (21.9%) tested positive for anti-hepatitis E virus (HEV) immunoglobulin G. Among 208 recipients tested by plasma/serum HEV polymerase chain reaction (2012-2022), 3 (1.4%) primary HEV infections were diagnosed; in 1 patient, plasma HEV polymerase chain reaction relapsed positive for 100 days. HEV infection remains rare albeit associated with persistent viral replication.

Keywords

Acute hepatitis E
Allogeneic hematopoietic cell transplantation
Hepatitis E virus
Immunosuppression
Seroprevalance

Affiliation

Faculté de médecine / Section de médecine clinique / Département de médecine

Research group

Citation (ISO format)

COURJON, Johan et al. Hepatitis E Virus Infection Epidemiology in Recipients of Allogeneic Hematopoietic Cell Transplant. In: Open forum infectious diseases, 2023, vol. 10, n° 12, p. ofad595. doi: 10.1093/ofid/ofad595

Article (Published version)

accessLevelPublic

Identifiers

PID : unige:178172
DOI : 10.1093/ofid/ofad595
PMID : 38094666
PMCID : PMC10716736

Commercial URLhttps://academic.oup.com/ofid/article/10/12/ofad595/7450156

ISSN of the journal2328-8957

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