Scientific article
Case report
Open access

Langerhans Cell Histiocytosis of the Suprasellar Region : Diagnosis on Thyroid Cytology

Published inEuropean thyroid journal, vol. 13, no. 3, e240011
Publication date2024-05-01
First online date2024-05-01

Langerhans cell histiocytosis (LCH) may present as unifocal disease of the suprasellar region, with symptoms and signs of hypopituitarism, arginine vasopressin deficiency (AVP-D) and weight gain. Transcranial biopsy is necessary, to define diagnosis and guide treatment decisions, but is associated with significant morbidity. We describe a patient with Hashimoto thyroiditis and a single hypothalamic mass in whom LCH diagnosis was done through thyroid fine-needle aspiration cytology (FNAC) performed despite nonspecific findings in thyroid imaging, on the basis of a slightly elevated [18F]-fluorodeoxyglucose avidity on positron emission tomography/-computed tomography (FDG-PET/-CT), and volume increase during follow-up.

  • Histiocytosis
  • Hypothalamic lesion
  • Thyroid FNA
Citation (ISO format)
MAVROMATI, Maria et al. Langerhans Cell Histiocytosis of the Suprasellar Region : Diagnosis on Thyroid Cytology. In: European thyroid journal, 2024, vol. 13, n° 3, p. e240011. doi: 10.1530/ETJ-24-0011
Main files (2)
Article (Published version)
Article (Accepted version)
ISSN of the journal2235-0640

Technical informations

Creation05/23/2024 11:33:33 AM
First validation06/12/2024 1:37:00 PM
Update time06/12/2024 1:37:00 PM
Status update06/12/2024 1:37:00 PM
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