Scientific article

The arguments for pre-existing early and late endosomes

Published inTrends in cell biology, vol. 1, no. 1, p. 5-9
Publication date1991-07

The past decade has seen the elucidation of many of the events and processes responsible for receptor-mediated endocytosis. However, a fundamental question about the endocytic pathway remains unresolved: do early endosomes mature into late endosomes, or are these two distinct and pre-existing cellular organelles? General opinion tends to favour the former possibility, to the point where one poster session at the recent American Society for Cell Biology meeting* was entitled 'Maturation of Endosomes'. This article draws together new data arguing in favour of pre-existing early and late endosomes, between which transport occurs by vesicle budding and fusion.

Citation (ISO format)
GRIFFITHS, Gareth, GRUENBERG, Jean. The arguments for pre-existing early and late endosomes. In: Trends in cell biology, 1991, vol. 1, n° 1, p. 5–9. doi: 10.1016/0962-8924(91)90047-D
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Article (Published version)
ISSN of the journal0962-8924

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