en
Scientific article
English

Conformationally Stabilized Catalysts by Fluorine Insertion: Tool for Enantioselectivity Improvement

Published inChemistry, vol. 17, no. 48, p. 13433-13437
Publication date2011
Abstract

F rigid cats: The power of conformationally stabilized catalysts is demonstrated. By taking appropriate advantage of fluorine insertion (see scheme), purely conformational catalyst design led to a notable improvement in enantioselectivities from around 70 % to 91–98.5 % ee. The other advantage of this approach is the better understanding of the origin of the stereoselectivity in the given catalytic system.

Citation (ISO format)
QUINTARD, Adrien et al. Conformationally Stabilized Catalysts by Fluorine Insertion: Tool for Enantioselectivity Improvement. In: Chemistry, 2011, vol. 17, n° 48, p. 13433–13437. doi: 10.1002/chem.201102757
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
ISSN of the journal0947-6539
575views
0downloads

Technical informations

Creation12/05/2011 2:28:00 PM
First validation12/05/2011 2:28:00 PM
Update time03/14/2023 5:05:29 PM
Status update03/14/2023 5:05:29 PM
Last indexation01/15/2024 10:48:12 PM
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack